Intraindividual variation in serum thyroid hormones, parathyroid hormone and insulin-like growth factor-1

被引：44

作者：

Ankrah-Tetteh, T. ^{[1
]}

Wijeratne, S. ^{[1
]}

Swaminathan, R. ^{[1
]}

机构：

[1] St Thomas Hosp, Dept Chem Pathol, London SE1 7EH, England

来源：

ANNALS OF CLINICAL BIOCHEMISTRY | 2008年 / 45卷

关键词：

D O I：

10.1258/acb.2007.007103

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Background: Biological variation of an analyte is an important determinant of its usefulness. Intraindividual variation in serum thyroid hormones, parathyroid hormone (PTH) and insulin-like growth factor-1 (IGF-1) in healthy subjects was determined in this study. Methods: Blood samples were taken at weekly intervals for six weeks from 10 healthy subjects and analysed for serum thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triioclothyronine (FT3), PTH and IGF-1. Results: Intraindividual variations for serum FT4 and FT3 were <5.0%, IGF-1 9.4% and TSH and PTH 25.1% and 25.9%, respectively. Index of individuality was lowest for FT4 (0.42) and FT3 (0.38), and highest for IPTH (1.09). Conclusion: Intraindividual variation for FT4, FT3 and IGF-1 are low.

引用

页码：167 / 169

页数：3

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