Factors influencing the migration of bisphenol A from cans

The objective of this study was to determine whether there is a relationship between bisphenol A (BPA) migration from metal cans and container contents (glucose, sodium chloride, and vegetable oil), heating time, and/or temperature. Cans containing 5 to 20% glucose solution, 1 to 10% sodium chloride solution, and vegetable oils (corn, olive, and soybean oil) were heated at 121degreesC for 30 min. Water samples were heated at 105degreesC for 30 min and at 121degreesC for 15, 30, and 60 min, respectively. In the test involving water samples, it was found that temperature's effect on BPA migration from cans can be more extensive than that of heating time. When cans were heated at 121degreesC, the presence of 1 to 10% sodium chloride or vegetable oils greatly increased the migration of BPA from the cans. Moreover, the presence of 5 to 20% glucose in cans heated to 121degreesC resulted in increased BPA migration relative to that for water controls.