Predictive factors for successful sacral nerve stimulation in the treatment of faecal incontinence: a 10-year cohort analysis

被引:97
作者
Dudding, T. C. [1 ]
Pares, D. [1 ]
Vaizey, C. J. [1 ]
Kamm, M. A. [1 ]
机构
[1] St Marks Hosp, Physiol Unit, London EC1V 2PS, England
关键词
sacral nerve stimulation; neuromodulation; faecal incontinence; predictive value of tests; surgery; obstetric;
D O I
10.1111/j.1463-1318.2007.01319.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objective Sacral nerve stimulation (SNS) is an established treatment for faecal incontinence. We aimed to identify specific factors that could predict the outcome of temporary and permanent stimulation. Method A cohort analysis was performed to identify potential predictive factors in 81 patients who underwent temporary SNS at a single institution over a 10-year period (June 1996 to June 2006). Data were obtained from prospectively collected patient symptom diaries and quality of life questionnaires, operation reports, anorectal physiological studies, endoanal ultrasound images and radiology of lead placement. Results Clinical outcome of temporary screening was not affected by patient gender, age, body mass index, severity or length of symptoms. The need for a repeated temporary procedure was associated with subsequent failure during screening (P = 0.008). A low threshold to obtain a motor response during temporary lead insertion was associated with improved outcome (P = 0.048). Evidence of anal sphincter trauma was associated with a greater risk of failure (P = 0.040). However, there was no difference in medium-term outcome between patients with external anal sphincter (EAS) defects and patients with intact anal sphincter muscles. Conclusion Variables have been identified that help to predict the outcome of SNS. The presence of an EAS defect should not preclude treatment.
引用
收藏
页码:249 / 256
页数:8
相关论文
共 23 条
[1]   Reliability of electrophysiologic anal tests in predicting the outcome of sacral nerve modulation for fecal incontinence [J].
Altomare, DF ;
Rinaldi, M ;
Petrolino, M ;
Ripetti, V ;
Masin, A ;
Ratto, C ;
Trerotoli, P ;
Monitillo, V ;
Lobascio, P ;
De Fazio, M ;
Guglielmi, A ;
Memeo, V .
DISEASES OF THE COLON & RECTUM, 2004, 47 (06) :853-857
[2]   Permanent sacral nerve modulation for fecal incontinence and associated urinary disturbances [J].
Altomare, DF ;
Rinaldi, M ;
Petrolino, M ;
Monitillo, V ;
Sallustio, P ;
Veglia, A ;
De Fazio, M ;
Guglielmi, A ;
Memeo, V .
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2004, 19 (03) :203-209
[3]  
ALTOMARE DF, 2004, EUR COUNC COL EUR AS
[4]   Sacral nerve stimulation results may be improved by electrodiagnostic techniques [J].
Benson, JT .
INTERNATIONAL UROGYNECOLOGY JOURNAL AND PELVIC FLOOR DYSFUNCTION, 2000, 11 (06) :352-357
[5]   Sacral nerve stimulation can be successful in patients with ultrasound evidence of external anal sphincter disruption [J].
Conaghan, P ;
Farouk, R .
DISEASES OF THE COLON & RECTUM, 2005, 48 (08) :1610-1614
[6]   Functional asymmetry of pelvic floor innervation and its role in the pathogenesis of fecal incontinence [J].
Enck, P ;
Hinninghofen, H ;
Wietek, B ;
Becker, HD .
DIGESTION, 2004, 69 (02) :102-111
[7]   Studies of the latency of pelvic floor contraction during peripheral nerve evaluation show that the muscle response is reflexly mediated [J].
Fowler, CJ ;
Swinn, MJ ;
Goodwin, RJ ;
Oliver, S ;
Craggs, M .
JOURNAL OF UROLOGY, 2000, 163 (03) :881-883
[8]   Preservation of pudendal afferents in sacral rhizotomies [J].
Huang, JC ;
Deletis, V ;
Vodusek, DB ;
Abbott, R .
NEUROSURGERY, 1997, 41 (02) :411-415
[9]   Systematic review of sacral nerve stimulation for faecal incontinence and constipation [J].
Jarrett, MED ;
Mowatt, G ;
Glazener, CMA ;
Fraser, C ;
Nicholls, RJ ;
Grant, AM ;
Kamm, MA .
BRITISH JOURNAL OF SURGERY, 2004, 91 (12) :1559-1569
[10]   Sacral nerve stimulation for faecal incontinence in the UK [J].
Jarrett, MED ;
Varma, JS ;
Duthie, GS ;
Nicholls, RJ ;
Kamm, MA .
BRITISH JOURNAL OF SURGERY, 2004, 91 (06) :755-761