CyClus3D: a Cytoscape plugin for clustering network motifs in integrated networks

被引:11
作者
Audenaert, Pieter [2 ]
Van Parys, Thomas [3 ,4 ]
Brondel, Florian [2 ]
Pickavet, Mario [2 ]
Demeester, Piet [2 ]
Van de Peer, Yves [3 ,4 ]
Michoel, Tom [1 ]
机构
[1] Univ Freiburg, Sch Life Sci LifeNet, Freiburg Inst Adv Studies, D-79104 Freiburg, Germany
[2] Univ Ghent, IBBT, Dept Informat Technol, B-9050 Ghent, Belgium
[3] Univ Ghent VIB, Dept Plant Syst Biol, B-9052 Ghent, Belgium
[4] Univ Ghent, Dept Plant Biotechnol & Genet, B-9052 Ghent, Belgium
关键词
YEAST; ORGANIZATION; PRINCIPLES;
D O I
10.1093/bioinformatics/btr182
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Network motifs in integrated molecular networks represent functional relationships between distinct data types. They aggregate to form dense topological structures corresponding to functional modules which cannot be detected by traditional graph clustering algorithms. We developed CyClus3D, a Cytoscape plugin for clustering composite three-node network motifs using a 3D spectral clustering algorithm. © The Author 2011. Published by Oxford University Press. All rights reserved.
引用
收藏
页码:1587 / 1588
页数:2
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