Alginate-Collagen Fibril Composite Hydrogel

被引：83

作者：

Baniasadi, Mahmoud ^{[1
]}

Minary-Jolandan, Majid ^{[1
]}

机构：

[1] Univ Texas Dallas, Dept Mech Engn, Richardson, TX 75080 USA

来源：

MATERIALS | 2015年 / 8卷 / 02期

关键词：

NANOCOMPOSITE HYDROGELS; OSTEOGENIC DIFFERENTIATION; SCAFFOLDS; CONSTRUCTS; MODULUS; DESIGN;

D O I：

10.3390/ma8020799

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

We report on the synthesis and the mechanical characterization of an alginate-collagen fibril composite hydrogel. Native type I collagen fibrils were used to synthesize the fibrous composite hydrogel. We characterized the mechanical properties of the fabricated fibrous hydrogel using tensile testing; rheometry and atomic force microscope (AFM)-based nanoindentation experiments. The results show that addition of type I collagen fibrils improves the rheological and indentation properties of the hydrogel.

引用

页码：799 / 814

页数：16

共 67 条

[1]

Strong fiber-reinforced hydrogel [J].

Agrawal, Animesh ;

Rahbar, Nima ;

Calvert, Paul D. .

ACTA BIOMATERIALIA, 2013, 9 (02) :5313-5318

[2]

Slicing, Stacking and Rolling: Fabrication of Nanostructured Collagen Constructs from Tendon Sections [J].

Alberti, Kyle A. ;

Xu, Qiaobing .

ADVANCED HEALTHCARE MATERIALS, 2013, 2 (06) :817-821

[3]

25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine [J].

Annabi, Nasim ;

Tamayol, Ali ;

Uquillas, Jorge Alfredo ;

Akbari, Mohsen ;

Bertassoni, Luiz E. ;

Cha, Chaenyung ;

Camci-Unal, Gulden ;

Dokmeci, Mehmet R. ;

Peppas, Nicholas A. ;

Khademhosseini, Ali .

ADVANCED MATERIALS, 2014, 26 (01) :85-124

[4]

Alginate hydrogels as biomaterials [J].

Augst, Alexander D. ;

Kong, Hyun Joon ;

Mooney, David J. .

MACROMOLECULAR BIOSCIENCE, 2006, 6 (08) :623-633

[5]

Nanoparticle polymer composites: Where two small worlds meet [J].

Balazs, Anna C. ;

Emrick, Todd ;

Russell, Thomas P. .

SCIENCE, 2006, 314 (5802) :1107-1110

[6]

Nano-biocomposites: Biodegradable polyester/nanoclay systems [J].

Bordes, Perrine ;

Pollet, Eric ;

Averous, Luc .

PROGRESS IN POLYMER SCIENCE, 2009, 34 (02) :125-155

[7]

Carbon-Based Nanomaterials: Multifunctional Materials for Biomedical Engineering [J].

Cha, Chaenyung ;

Shin, Su Ryon ;

Annabi, Nasim ;

Dokmeci, Mehmet R. ;

Khademhosseini, Ali .

ACS NANO, 2013, 7 (04) :2891-2897

[8]

Biomimetic collagen scaffolds with anisotropic pore architecture [J].

Davidenko, N. ;

Gibb, T. ;

Schuster, C. ;

Best, S. M. ;

Campbell, J. J. ;

Watson, C. J. ;

Cameron, R. E. .

ACTA BIOMATERIALIA, 2012, 8 (02) :667-676

[9]

The tensile properties of alginate hydrogels [J].

Drury, JL ;

Dennis, RG ;

Mooney, DJ .

BIOMATERIALS, 2004, 25 (16) :3187-3199

[10]

Hydrogels for tissue engineering: scaffold design variables and applications [J].

Drury, JL ;

Mooney, DJ .

BIOMATERIALS, 2003, 24 (24) :4337-4351

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