Development and characterization of a disposable electrochemical detector arrangement for capillary electrophoresis prepared by thermal lamination

A disposable electrochemical detector arrangement for capillary electrophoresis has been developed. The detection system consists of an assembly of a fused silica capillary and a microfiber electrode which are fixed in a proper position by sealing this configuration with the help of thermal lamination. The detector design is easy to prepare and inexpensive. Therefore it is used as a disposable device which can be replaced by a new one if any degradation of the performance characteristics occurs. The parameters influencing the detection performance were studied and optimized using nonaqueous capillary electrophoresis and ferrocene derivatives as model compounds. The practical utility was demonstrated by studying the separation and detection of water-resistant dye compounds.