MicroRNAs make big impression in disease after disease

被引:95
作者
Couzin, Jennifer
机构
关键词
D O I
10.1126/science.319.5871.1782
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Lately, microRNAs are garnering attention on the biomedical front, startling researchers with ever-expanding roles in disease. Studies show that microRNAs may offer a window into the development of various ailments, including cancer, diabetes, and heart failure, and provide a chance to strike disease targets that until now were unreachable. When poorly regulated, the molecules appear to drive cancer and a host of other diseases, and this could make them useful in diagnosing disease very early. MicroRNAs made by viruses, meanwhile, may help pathogens gain a foothold in their host, which could suggest new targets for antiviral drugs. MicroRNA-based therapeutic strategies are currently being considered.
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页码:1782 / 1784
页数:3
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