Bile Infarcts: New Insights Into the Pathogenesis of Obstructive Cholestasis

被引:8
作者
Cai, Shi-ying [1 ]
Boyer, James L. [1 ]
机构
[1] Yale Univ, Sch Med, Ctr Liver, New Haven, CT 06510 USA
关键词
D O I
10.1002/hep.30291
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:473 / 475
页数:3
相关论文
共 10 条
[1]
Bile Acids Induce Inflammatory Genes in Hepatocytes A Novel Mechanism of Inflammation during Obstructive Cholestasis [J].
Allen, Katryn ;
Jaeschke, Hartmut ;
Copple, Bryan L. .
AMERICAN JOURNAL OF PATHOLOGY, 2011, 178 (01) :175-186
[2]
Boyer JL, 2019, THE LIVER
[3]
Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response [J].
Cai, Shi-Ying ;
Ouyang, Xinshou ;
Chen, Yonglin ;
Soroka, Carol J. ;
Wang, Juxian ;
Mennone, Albert ;
Wang, Yucheng ;
Mehal, Wajahat Z. ;
Jain, Dhanpat ;
Boyer, James L. .
JCI INSIGHT, 2017, 2 (05)
[4]
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles [J].
Fickert, P ;
Zollner, G ;
Fuchsbichler, A ;
Stumptner, C ;
Weiglein, AH ;
Lammert, F ;
Marschall, HU ;
Tsybrovskyy, O ;
Zatloukal, K ;
Denk, H ;
Trauner, M .
GASTROENTEROLOGY, 2002, 123 (04) :1238-1251
[5]
Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood [J].
Ghallab, Ahmed ;
Hofmann, Ute ;
Sezgin, Selahaddin ;
Vartak, Nachiket ;
Hassan, Reham ;
Zaza, Ayham ;
Godoy, Patricio ;
Schneider, Kai Markus ;
Guenther, Georgia ;
Ahmed, Yasser A. ;
Abbas, Aya A. ;
Keitel, Verena ;
Kuepfer, Lars ;
Dooley, Steven ;
Lammert, Frank ;
Trautwein, Christian ;
Spiteller, Michael ;
Drasdo, Dirk ;
Hofmann, Alan F. ;
Jansen, Peter L. M. ;
Hengstler, Jan G. ;
Reif, Raymond .
HEPATOLOGY, 2019, 69 (02) :666-683
[6]
Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice [J].
Gujral, JS ;
Farhood, A ;
Bajt, ML ;
Jaeschke, H .
HEPATOLOGY, 2003, 38 (02) :355-363
[7]
Actomyosin contractility drives bile regurgitation as an early response during obstructive cholestasis [J].
Gupta, Kapish ;
Li, Qiushi ;
Fan, Jun Jun ;
Fong, Eliza Li Shan ;
Song, Ziwei ;
Mo, Shupei ;
Tang, Haoyu ;
Ng, Inn Chuan ;
Ng, Chan Way ;
Pawijit, Pornteera ;
Zhuo, Shuangmu ;
Dong, Chen-Yuan ;
Low, Boon Chuan ;
Wee, Aileen ;
Dan, Yock Young ;
Kanchanawong, Pakorn ;
So, Peter ;
Viasnoff, Virgile ;
Yu, Hanry .
JOURNAL OF HEPATOLOGY, 2017, 66 (06) :1231-1240
[8]
Early growth response factor-1 is critical for cholestatic liver injury [J].
Kim, ND ;
Moon, JO ;
Slitt, AL ;
Copple, BL .
TOXICOLOGICAL SCIENCES, 2006, 90 (02) :586-595
[9]
Structure-function correlation of tight junctional impairment after intrahepatic and extrahepatic cholestasis in rat liver [J].
Rahner, C ;
Stieger, B ;
Landmann, LA .
GASTROENTEROLOGY, 1996, 110 (05) :1564-1578
[10]
Effect of bile duct ligation on bile acid composition in mouse serum and liver [J].
Zhang, Youcai ;
Hong, Ji-Young ;
Rockwell, Cheryl E. ;
Copple, Bryan L. ;
Jaeschke, Hartmut ;
Klaassen, Curtis D. .
LIVER INTERNATIONAL, 2012, 32 (01) :58-69