A new microorganism for highly stereospecific Baeyer-Villiger oxidation of prochiral cyclobutanones

被引:22
作者
Alphand, V [1 ]
Mazzini, C [1 ]
Lebreton, J [1 ]
Furstoss, R [1 ]
机构
[1] Univ Mediterranee, Fac Sci Luminy, ERS CNRS 157, Grp Biocatalyse & Chim Fine, F-13288 Marseille 9, France
关键词
Baeyer-Villiger oxidation; prochiral cyclobutanone; Cunninghamella echinulata;
D O I
10.1016/S1381-1177(98)00038-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Baeyer-Villiger biooxidation of prochiral 3-substituted cyclobutanones were carried out using the fungus Cunninghamella echinulata. beta-substituted gamma-butyrolactones were thus obtained in high ees tee greater than or equal to 98%). These results were compared with those obtained using two Acinetobacter strains. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:219 / 221
页数:3
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