QT interval analysis on ambulatory electrocardiogram recordings: a selective beat averaging approach

被引:66
作者
Badilini, F
Maison-Blanche, P
Childers, R
Coumel, P
机构
[1] Hop Lariboisiere, Serv Cardiol, F-75010 Paris, France
[2] Univ Chicago, Med Ctr, Cardiol Sect, Chicago, IL 60637 USA
关键词
QT interval; ambulatory ECG recordings; selective beat averaging; QT/RR relation;
D O I
10.1007/BF02513269
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
A computerised method for the analysis of QT intervals in ambulatory ECG recordings is presented. This approach is based on selective beat averaging which allows one to process P-QRS-T complexes together with the environment that characterises them. Long-term autonomic nervous system influences are accounted for by separating the analysis over different circadian periods. Effects of QT recovery time are taken into account by requiring a stable heart rate preceding each beat to be averaged. Before averaging, beats are resampled and realigned with respect to the R-wave peak estimated by parabolic interpolation. Averaged ECG templates are then analysed with an algorithm which automatically detects QRS complex and T-wave features. Repolarisation analysis is based on first and second derivatives of lowpass filtered ECG (recursive Butterworth filter). The QT/RR relationship and the circadian QT variation at identical heart rate were analysed in 14 normal individuals. When performed at stable heart rate conditions and when confined to well-defined circadian periods, the QT/RR relationship was strongly linear (r = 0.95 +/- 0.06); in addition, the slope of this relation changed between day and night (respectively, 0.197 +/- 0.07 and 0.139 +/- 0.03, p < 0.01). The range of circadian QT variation at identical heart rate was approximately 20 ms for both males and females.
引用
收藏
页码:71 / 79
页数:9
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