Carbon-encapsulated radioactive 99mTc nanoparticles

被引：30

作者：

Chan, HBS

Ellis, BL

Sharma, HL

Frost, W

Caps, V

Shields, RA

Tsang, SC ^{[1
]}

机构：

[1] Univ Reading, Surface & Catalysis Res Ctr, Sch Chem, Reading RG6 6AD, Berks, England

[2] Univ Manchester, Dept Imaging Sci, Manchester M13 9PT, Lancs, England

[3] Manchester Royal Infirm, Dept Nucl Med & Med Phys, Manchester M13 9WL, Lancs, England

来源：

ADVANCED MATERIALS | 2004年 / 16卷 / 02期

关键词：

D O I：

10.1002/adma.200305407

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A macroscopic quantity of quasi-spherical fullerene-like shells (see Figure) that encapsulate iron nanoparticles containing radioisotope Tc-99m are prepared for the first time. The nanocomposite is acid-non-leachable, retaining radioactivity at an extremely high level. This method will enable rigorous studies of what are currently theoretical descriptions of nanometer-scale medicinal delivery vehicles for diagnostic and therapeutic purposes.

引用

收藏

页码：144 / +

页数：7

相关论文

共 17 条

[1] FORMATION OF FILAMENTOUS CARBON FROM IRON, COBALT AND CHROMIUM CATALYZED DECOMPOSITION OF ACETYLENE [J].

BAKER, RTK ;

HARRIS, PS ;

THOMAS, RB ;

WAITE, RJ .

JOURNAL OF CATALYSIS, 1973, 30 (01) :86-95

[2]

BURCH WM, 1996, NUCL MED COMMUN, V17, P865

[3] Reduction of pertechnetate by ferrous iron in solution: Influence of sorbed and precipitated Fe(II) [J].

Cui, DQ ;

Eriksen, TE .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1996, 30 (07) :2259-2262

[4] URANIUM STABILIZATION OF C28 - A TETRAVALENT FULLERENE [J].

GUO, T ;

DIENER, MD ;

CHAI, Y ;

ALFORD, MJ ;

HAUFLER, RE ;

MCCLURE, SM ;

OHNO, T ;

WEAVER, JH ;

SCUSERIA, GE ;

SMALLEY, RE .

SCIENCE, 1992, 257 (5077) :1661-1664

[5]

HARRIS PJF, 1999, CARBON NANOTUBES REL, pCH5

[6] THE FORMATION OF LONG CARBON CHAIN MOLECULES DURING LASER VAPORIZATION OF GRAPHITE [J].

HEATH, JR ;

ZHANG, Q ;

OBRIEN, SC ;

CURL, RF ;

KROTO, HW ;

SMALLEY, RE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (02) :359-363

[7] EVALUATION OF 99TCM TECHNEGAS VENTILATION SCINTIGRAPHY IN THE DIAGNOSIS OF PULMONARY-EMBOLISM [J].

JAMES, JM ;

HERMAN, KJ ;

LLOYD, JJ ;

SHIELDS, RA ;

TESTA, HJ ;

CHURCH, S ;

STRETTON, TB .

BRITISH JOURNAL OF RADIOLOGY, 1991, 64 (764) :711-719

[8]

JONES DEH, 1996, NEW SCI, V17, P354

[9] ENCAPSULATION OF RADIOACTIVE GD-159 AND TB-161 ATOMS IN FULLERENE CAGES [J].

KIKUCHI, K ;

KOBAYASHI, K ;

SUEKI, K ;

SUZUKI, S ;

NAKAHARA, H ;

ACHIBA, Y ;

TOMURA, K ;

KATADA, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (21) :9775-9776

[10] Thermal-induced microstructural changes of nickel-iron cyanide [J].

Ng, CW ;

Ding, J ;

Wang, L ;

Gan, LM ;

Quek, CH .

JOURNAL OF PHYSICAL CHEMISTRY A, 2000, 104 (38) :8814-8822