学术探索
学术期刊
学术作者
新闻热点
数据分析
智能评审

In Vivo Assessment of Bone Ingrowth Potential of Three-Dimensional E-Beam Produced Implant Surfaces and the Effect of Additional Treatment by Acid Etching and Hydroxyapatite Coating

被引：9
作者：
Biemond, J. Elizabeth [1 ]
Hannink, Gerjon [1 ]
Jurrius, Annemarijn M. G. [1 ]
Verdonschot, Nico [1 ,2 ]
Buma, Pieter [1 ]
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Orthopaed Res Lab, NL-6500 HB Nijmegen, Netherlands
[2] Univ Twente, Lab Biomech Engn, NL-7500 AE Enschede, Netherlands
来源：
JOURNAL OF BIOMATERIALS APPLICATIONS | 2012年 / 26卷 / 07期
关键词：
bone ingrowth; E-beam; hydroxyapatite; acid etching; surface characterization; in vivo; TOTAL HIP-ARTHROPLASTY; ETCHED MICROTEXTURE; TITANIUM IMPLANTS; METAL IMPLANTS; GROWTH; ENHANCEMENT; INTERFACE; SCAFFOLDS; POROSITY;
D O I：
10.1177/0885328210391495
中图分类号：
R318 [生物医学工程];
学科分类号：
100103 [病原生物学];
摘要：
The bone ingrowth potential of three-dimensional E-beam-produced implant surfaces was examined by histology and compared to a porous plasma-sprayed control. The effects of acid etching and a hydroxyapatite (HA) coating were also evaluated by histology. Specimens were implanted in the distal femur of 10 goats. Histological analysis of bone ingrowth was performed 6 weeks after implantation. The E-beam-produced surfaces showed significantly better bone ingrowth compared to the plasma-sprayed control. Additional treatment of the E-beam surface structures with a HA coating, further improved bone ingrowth potential of these structures significantly. Acid etching of the E-beam structures did not influence bone ingrowth significantly. In conclusion, the HA-coated, E-beam-produced structures are promising potential implant surfaces.
引用
收藏
页码：861 / 875
页数：15
相关论文
共 21 条
[1]
Osteointegration of biomimetic apatite coating applied onto dense and porous metal implants in femurs of goats [J].
Barrère, F ;
van der Valk, CM ;
Meijer, G ;
Dalmeijer, RAJ ;
de Groot, K ;
Layrolle, P .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2003, 67B (01) :655-665
[2]
Osseointegration in arthroplasty: can simvastatin promote bone response to implants? [J].
Basarir, Kerem ;
Erdemli, Buelent ;
Can, Alp ;
Erdemli, Esra ;
Zeyrek, Tugba .
INTERNATIONAL ORTHOPAEDICS, 2009, 33 (03) :855-859
[3]
Characteristics of bone ingrowth and interface mechanics of a new porous tantalum biomaterial [J].
Bobyn, JD ;
Stackpool, GJ ;
Hacking, SA ;
Tanzer, M ;
Krygier, JJ .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1999, 81B (05) :907-914
[4]
Bone growth enhancement in vivo on press-fit titanium alloy implants with acid etched microtexture [J].
Daugaard, Henrik ;
Elmengaard, Brian ;
Bechtold, Joan E. ;
Soballe, Kjeld .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2008, 87A (02) :434-440
[5]
Davis J.R, 2005, HDB MAT MED DEVICES, P179
[6]
Uncemented total hip arthroplasty for primary osteoarthritis in young patients - A mid- to long-term follow-up study from the Finnish Arthroplasty Register [J].
Eskelinen, A ;
Remes, V ;
Helenius, I ;
Pulkkinen, P ;
Nevalainen, J ;
Paavolainen, P .
ACTA ORTHOPAEDICA, 2006, 77 (01) :57-70
[7]
Biomimetic hydroxyapatite coating on metal implants [J].
Habibovic, P ;
Barrère, F ;
van Blitterswijk, CA ;
de Groot, K ;
Layrolle, P .
JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 2002, 85 (03) :517-522
[8]
Acid-etched microtexture for enhancement of bone growth into porous-coated implants [J].
Hacking, SA ;
Harvey, EJ ;
Tanzer, M ;
Krygier, JJ ;
Bobyn, JD .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2003, 85B (08) :1182-1189
[9]
Cellular Ti-6Al-4V structures with interconnected macro porosity for bone implants fabricated by selective electron beam melting [J].
Heinl, Peter ;
Mueller, Lenka ;
Koerner, Carolin ;
Singer, Robert F. ;
Mueller, Frank A. .
ACTA BIOMATERIALIA, 2008, 4 (05) :1536-1544
[10]
Cellular titanium by selective electron beam melting [J].
Heinl, Peter ;
Rottmair, Andreas ;
Koerner, Carolin ;
Singer, Robert F. .
ADVANCED ENGINEERING MATERIALS, 2007, 9 (05) :360-364
123