Carbon nanotube-based biosensor

被引:133
作者
Wohlstadter, JN
Wilbur, JL
Sigal, GB
Biebuyck, HA
Billadeau, MA
Dong, LW
Fischer, AB
Gudibande, SR
Jamieson, SH
Kenten, JH
Leginus, J
Leland, JK
Massey, RJ
Wohlstadter, SJ
机构
[1] Meso Scale Diagnost LLC, Gaithersburg, MD 20877 USA
[2] IGEN Int Inc, Gaithersburg, MD 20877 USA
关键词
D O I
10.1002/adma.200304259
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Carbon nanotubes, compounded into plastic create bulk electrodes, form the basis of a novel sensor for biological assays. The nanotubes function as both a solid phase and working electrode for generation of electrochemiluminescence, the detection method used in this system. The Figure shows a scanning electron microscopy image of a composite used for an immunoassay. The bright spots in the image are 10 nm diameter gold colloids covalently attached to antibodies. The inset shows a region of a composite with no gold colloids.
引用
收藏
页码:1184 / +
页数:5
相关论文
共 37 条
  • [1] Carbon nanotubes: A thermoelectric nano-nose
    Adu, CKW
    Sumanasekera, GU
    Pradhan, BK
    Romero, HE
    Eklund, PC
    [J]. CHEMICAL PHYSICS LETTERS, 2001, 337 (1-3) : 31 - 35
  • [2] Nanotubes from carbon
    Ajayan, PM
    [J]. CHEMICAL REVIEWS, 1999, 99 (07) : 1787 - 1799
  • [3] [Anonymous], 2000, Encyclopedia of Analytical Chemistry
  • [4] Balavoine F, 1999, ANGEW CHEM INT EDIT, V38, P1912, DOI 10.1002/(SICI)1521-3773(19990712)38:13/14<1912::AID-ANIE1912>3.0.CO
  • [5] 2-2
  • [6] Carbon nanotube actuators
    Baughman, RH
    Cui, CX
    Zakhidov, AA
    Iqbal, Z
    Barisci, JN
    Spinks, GM
    Wallace, GG
    Mazzoldi, A
    De Rossi, D
    Rinzler, AG
    Jaschinski, O
    Roth, S
    Kertesz, M
    [J]. SCIENCE, 1999, 284 (5418) : 1340 - 1344
  • [7] BENING RC, 1990, POLYM PREPR AM CHEM, V30, P420
  • [8] Britto PJ, 1999, ADV MATER, V11, P154, DOI 10.1002/(SICI)1521-4095(199902)11:2<154::AID-ADMA154>3.0.CO
  • [9] 2-B
  • [10] Burtis C.A., 1994, Tietz Textbook of Clinical Chemistry