Acremonium pyomyositis in a pediatric patient with acute leukemia

被引:15
作者
Chang, YH
Huang, LM
Hsueh, PR
Hsiao, CH
Peng, SF
Yang, RS
Lin, KH
机构
[1] Natl Taiwan Univ Hosp, Dept Pediat, Coll Med, Taipei 10016, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Internal Med, Coll Med, Taipei 10016, Taiwan
[3] Natl Taiwan Univ Hosp, Dept Lab Med, Coll Med, Taipei 10016, Taiwan
[4] Natl Taiwan Univ Hosp, Dept Pathol, Coll Med, Taipei 10016, Taiwan
[5] Natl Taiwan Univ Hosp, Dept Radiol, Coll Med, Taipei 10016, Taiwan
[6] Natl Taiwan Univ Hosp, Dept Orthopaed, Coll Med, Taipei 10016, Taiwan
关键词
Acremonium; leukemia;
D O I
10.1002/pbc.20276
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Invasive Acremonium infection in humans is rare. We report a patient with leukemia who developed pyomyositis due to Acremonium species. Painful cutaneous nodules and severe myalgia were the first clinical manifestations during the neutropenic stage after chemotherapy. Magnetic resonance image (MRI) revealed multiple nodular lesions scattered along the intramuscular regions of the lower legs. Culture of an aspiration grew Acremonium species. Surgical drainage was performed. Although all antifungal agents tested showed no in vitro inhibitory activity, we successfully treated this patient with amphotericin 13, granulocyte colony-stimulating factor (G-CSF), and surgical drainage. (c) 2004 Wiley-Liss, Inc.
引用
收藏
页码:521 / 524
页数:4
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