Diagnosis and quantitation of fibrosis

被引：380

作者：

Manning, Diarmuid S. ^{[1
]}

Afdhal, Nezam H. ^{[1
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA

来源：

GASTROENTEROLOGY | 2008年 / 134卷 / 06期

关键词：

D O I：

10.1053/j.gastro.2008.03.001

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatic fibrosis is the final common pathway for many different liver insults. Originally considered to be irreversible, hepatic fibrosis is now known to be a dynamic process with a significant potential for resolution. The diagnosis and quantitation of fibrosis have traditionally relied on liver biopsy. However, there are a number of drawbacks including the invasive nature of the procedure, sampling error, and interobserver variability. This article reviews the current role of liver biopsy in the assessment of hepatic fibrosis and discusses the role of the newer noninvasive methods including serum markers and radiologic tests.

引用

页码：1670 / 1681

页数：12

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