Conformationally constrained bis(oxazoline) derived chiral catalyst: A highly effective enantioselective Diels-Alder reaction

被引：100

作者：

Ghosh, AK

Packiarajan, M

Cappiello, J

机构：

[1] Department of Chemistry, University of Illinois at Chicago, Chicago, IL 60607

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 22期

关键词：

D O I：

10.1016/0040-4039(96)00721-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of cyclopentadiene with various bidentate dienophiles in the presence of 4-10 mol% of copper(II)-bis(oxazoline) complexes afforded excellent endo/exo selectivity as well as endo enantioselectivity (95-99% ee) and isolated yields. On the other hand, Diels-Alder reaction with Mg(II)-complexes afforded a modest (61% ee) reversal in enantioselectivity. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：3815 / 3818

页数：4

共 38 条

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