The eosinophil ribonucleases

被引：72

作者：

Rosenberg, HF ^{[1
]}

机构：

[1] NIAID, Host Def Lab, NIH, Bethesda, MD 20892 USA

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 1998年 / 54卷 / 08期

关键词：

eosinophils; host defence; primates; rodents; evolution;

D O I：

10.1007/s000180050208

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The eosinophil ribonucleases, eosinophil-derived neurotoxin (EDN/RNase 2) and eosinophil cationic protein (ECP/RNase 3) are two closely related proteins with intriguing functional and evolutionary properties. While both EDN and ECP maintain the structural and catalytic residues typical of the RNase A superfamily, the role of ribonuclease activity in the physiologic function of these proteins remains unclear. The biochemistry and physiology of EDN, ECP and the recently discovered ribonuclease k6 (RNase 6) will be reviewed in this chapter.

引用

收藏

页码：795 / 803

页数：9

相关论文

共 95 条

[31] THE DNA-SEQUENCES OF THE HUMAN AND HAMSTER SECRETORY RIBONUCLEASES DETERMINED WITH THE POLYMERASE CHAIN-REACTION (PCR) [J].

HAUGG, M ;

SCHEIN, CH .

NUCLEIC ACIDS RESEARCH, 1992, 20 (03) :612-612

[32]

Hirsch JG, 1980, EOSINOPHIL HLTH DIS, P3

[33] PRIMARY STRUCTURE OF A NON-SECRETORY RIBONUCLEASE FROM BOVINE KIDNEY [J].

IRIE, M ;

NITTA, R ;

OHGI, K ;

NIWATA, Y ;

WATANABE, H ;

IWAMA, M ;

BEINTEMA, JJ ;

SANDA, A ;

TAKIZAWA, Y .

JOURNAL OF BIOCHEMISTRY, 1988, 104 (02) :289-296

[34] PURIFICATION AND PRIMARY STRUCTURE OF A PORCINE KIDNEY NONSECRETORY RIBONUCLEASE [J].

IWAMA, M ;

SANDA, A ;

OHGI, K ;

HOFSTEENGE, J ;

IRIE, M .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1993, 57 (12) :2133-2138

[35] CHARACTERIZATION OF UGP AND ITS RELATIONSHIP WITH BETA-CORE FRAGMENT [J].

KARDANA, A ;

BAGSHAWE, KD ;

COLES, B ;

READ, D ;

TAYLOR, M .

BRITISH JOURNAL OF CANCER, 1993, 67 (04) :686-692

[36]

KAY AB, 1990, EOSINOPHILS ALLERGY

[37] An ultrastructural study of the interaction of human eosinophils with respiratory syncytial virus [J].

Kimpen, JLL ;

Garofalo, R ;

Welliver, RC ;

Fujihara, K ;

Ogra, PL .

PEDIATRIC ALLERGY AND IMMUNOLOGY, 1996, 7 (01) :48-53

[38] ACTIVATION OF HUMAN EOSINOPHILS INVITRO BY RESPIRATORY SYNCYTIAL VIRUS [J].

KIMPEN, JLL ;

GAROFALO, R ;

WELLIVER, RC ;

OGRA, PL .

PEDIATRIC RESEARCH, 1992, 32 (02) :160-164

[39] Virucidal effect of stimulated eosinophils on human immunodeficiency virus type 1 [J].

Klebanoff, SJ ;

Coombs, RW .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1996, 12 (01) :25-29

[40] SEQUENCE OF THE CDNA AND GENE FOR ANGIOGENIN, A HUMAN ANGIOGENESIS FACTOR [J].

KURACHI, K ;

DAVIE, EW ;

STRYDOM, DJ ;

RIORDAN, JF ;

VALLEE, BL .

BIOCHEMISTRY, 1985, 24 (20) :5494-5499

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