Synthesis of a new water-soluble octa-cationic phthalocyanine derivative for PDT

被引:122
作者
De Filippis, MP [1 ]
Dei, D [1 ]
Fantetti, L [1 ]
Roncucci, G [1 ]
机构
[1] Molteni Farmaceut, I-50018 Florence, Italy
关键词
phthalocyanines; PDT; cationic photosensitizers;
D O I
10.1016/S0040-4039(00)01638-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis and characterization of a new octa-cationic Zn-phthalocyanine is described. This compound is water-soluble, not aggregated under a wide range of solvent conditions and is a powerful photosensitizer for the inactivation of microorganisms by using a strategy based on photodynamic therapy. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:9143 / 9147
页数:5
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