Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes The Korean Sarcopenic Obesity Study (KSOS)

被引：606

作者：

Kim, Tae Nyun ^{[1
]}

Park, Man Sik ^{[2
]}

Yang, Sae Jeong ^{[1
]}

Yoo, Hye Jin ^{[1
]}

Kang, Hyun Joo ^{[3
]}

Song, Wook ^{[4
]}

Seo, Ji A. ^{[1
]}

Kim, Sin Gon ^{[1
]}

Kim, Nan Hee ^{[1
]}

Baik, Sei Hyun ^{[1
]}

Choi, Dong Seop ^{[1
]}

Choi, Kyung Mook ^{[1
]}

机构：

[1] Korea Univ, Div Endocrinol & Metab, Dept Internal Med, Coll Med, Seoul, South Korea

[2] Sungshim Womens Univ, Coll Nat Sci, Dept Stat, Seoul, South Korea

[3] Soonchunhyang Univ, Div Phys Educ, A San, South Korea

[4] Seoul Natl Univ, Hlth & Exercise Sci Lab, Inst Sports Sci, Dept Phys Educ, Seoul, South Korea

来源：

DIABETES CARE | 2010年 / 33卷 / 07期

关键词：

SKELETAL-MUSCLE MASS; EPIDEMIOLOGY; ADULTS;

D O I：

10.2337/dc09-2310

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

OBJECTIVE - We examined prevalence of sarcopenia in Korean patients with type 2 diabetes and compared body compositional parameters between subjects with and without type 2 diabetes. RESEARCH DESIGN AND METHODS - The Korean Sarcopenic Obesity Study (KSOS) included 810 subjects (414 patients with diabetes and 396 control subjects) who were examined using dual-energy X-ray absorptiometry. Prevalence of sarcopenia was defined using the skeletal muscle index (SMI). RESULTS - Prevalence in patients with diabetes and in the control group was 15.7 and 6.9%, respectively. In both men and women, SMI values were significantly decreased in patients with diabetes compared with subjects without diabetes. Furthermore, multiple logistic regression analysis showed that type 2 diabetes was independently associated with sarcopenia. CONCLUSIONS - Type 2 diabetes was associated with increased risk of sarcopenia. These characteristics may contribute to physical disability and metabolic disorders in older adults with diabetes.

引用

页码：1497 / 1499

页数：3

共 12 条

[1]

Epidemiology of sarcopenia among the elderly in New Mexico [J].

Baumgartner, RN ;

Koehler, KM ;

Gallagher, D ;

Romero, L ;

Heymsfield, SB ;

Ross, RR ;

Garry, PJ ;

Lindeman, RD .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 1998, 147 (08) :755-763

[2]

Diabetes in Asia Epidemiology, Risk Factors, and Pathophysiology [J].

Chan, Juliana C. N. ;

Malik, Vasanti ;

Jia, Weiping ;

Kadowaki, Takashi ;

Yajnik, Chittaranjan S. ;

Yoon, Kun-Ho ;

Hu, Frank B. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 301 (20) :2129-2140

[3]

Appendicular skeletal muscle mass: Effects of age, gender, and ethnicity [J].

Gallagher, D ;

Visser, M ;

deMeersman, RE ;

Sepulveda, D ;

Baumgartner, RN ;

Pierson, RN ;

Harris, T ;

Heymsfield, SB .

JOURNAL OF APPLIED PHYSIOLOGY, 1997, 83 (01) :229-239

[4]

BODY-COMPOSITION OF HUMANS - COMPARISON OF 2 IMPROVED 4-COMPARTMENT MODELS THAT DIFFER IN EXPENSE, TECHNICAL COMPLEXITY, AND RADIATION EXPOSURE [J].

HEYMSFIELD, SB ;

LICHTMAN, S ;

BAUMGARTNER, RN ;

WANG, J ;

KAMEN, Y ;

ALIPRANTIS, A ;

PIERSON, RN .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1990, 52 (01) :52-58

[5]

Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability [J].

Janssen, I ;

Heymsfield, SB ;

Ross, R .

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (05) :889-896

[6]

Janssen I, 2000, J APPL PHYSIOL, V89, P81

[7]

Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method [J].

Kim, J ;

Wang, ZM ;

Heymsfield, SB ;

Baumgartner, RN ;

Gallagher, D .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2002, 76 (02) :378-383

[8]

Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study [J].

Kim, T. N. ;

Yang, S. J. ;

Yoo, H. J. ;

Lim, K. I. ;

Kang, H. J. ;

Song, W. ;

Seo, J. A. ;

Kim, S. G. ;

Kim, N. H. ;

Baik, S. H. ;

Choi, D. S. ;

Choi, K. M. .

INTERNATIONAL JOURNAL OF OBESITY, 2009, 33 (08) :885-892

[9]

Decreased muscle strength and quality in older adults with type 2 diabetes - The health, aging, and body composition study [J].

Park, Seok Won ;

Goodpaster, Bret H. ;

Strotmeyer, Elsa S. ;

de Rekeneire, Nathalie ;

Harris, Tamara B. ;

Schwartz, Ann V. ;

Tylavsky, Frances A. ;

Newman, Anne B. .

DIABETES, 2006, 55 (06) :1813-1818

[10]

Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes [J].

Park, Seok Won ;

Goodpaster, Bret H. ;

Lee, Jung Sun ;

Kuller, Lewis H. ;

Boudreau, Robert ;

de Rekeneire, Nathalie ;

Harris, Tamara B. ;

Kritchevsky, Stephen ;

Tylavsky, Frances A. ;

Nevitt, Michael ;

Cho, Yong-wook ;

Newman, Anne B. .

DIABETES CARE, 2009, 32 (11) :1993-1997

← 1 2 →