New mutations and intellectual function

被引：29

作者：

Lupski, James R. ^{[1
,2
]}

机构：

[1] Texas Childrens Hosp, Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA

[2] Texas Childrens Hosp, Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA

来源：

NATURE GENETICS | 2010年 / 42卷 / 12期

关键词：

REARRANGEMENTS; MOSAICISM; MECHANISM;

D O I：

10.1038/ng1210-1036

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Exome-based sequencing is a powerful approach for studying rare genetic diseases. A new study now applies this technology to demonstrate an important role for de novo mutations in sporadic mental retardation.

引用

页码：1036 / 1038

页数：4

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