Cancer - Inflammation by remote control

被引：251

作者：

Mantovani, A

机构：

[1] Ist Ric Farmacol Mario Negri, I-20157 Milan, Italy

[2] Univ Milan, Milan, Italy

来源：

NATURE | 2005年 / 435卷 / 7043期

关键词：

D O I：

10.1038/435752a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Smouldering beneath many latent tumours is a chronic inflammation that goads pre-malignant cells into becoming full-blown cancer. The spark that kindles these flames comes from an unexpected source.

引用

页码：752 / 753

页数：2

共 12 条

[1] Smoldering and polarized inflammation in the initiation and promotion of malignant disease
Balkwill, F
Charles, KA
Mantovani, A
[J]. CANCER CELL, 2005, 7 (03) : 211 - 217
[2] Inflammation and cancer: back to Virchow?
Balkwill, F
Mantovani, A
[J]. LANCET, 2001, 357 (9255) : 539 - 545
[3] Selective targeted delivery of TNFα to tumor blood vessels
Borsi, L
Balza, E
Carnemolla, B
Sassi, F
Castellani, P
Berndt, A
Kosmehl, H
Bir, A
Siri, A
Orecchia, P
Grassi, J
Ned, D
Zardi, L
[J]. BLOOD, 2003, 102 (13) : 4384 - 4392
[4] Inflammation and cancer
Coussens, LM
Werb, Z
[J]. NATURE, 2002, 420 (6917) : 860 - 867
[5] MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
Coussens, LM
Tinkle, CL
Hanahan, D
Werb, Z
[J]. CELL, 2000, 103 (03) : 481 - 490
[6] De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
de Visser, KE
Korets, LV
Coussens, LM
[J]. CANCER CELL, 2005, 7 (05) : 411 - 423
[7] The immunobiology of cancer immunosurveillance and immunoediting
Dunn, GP
Old, LJ
Schreiber, RD
[J]. IMMUNITY, 2004, 21 (02) : 137 - 148
[8] IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
Greten, FR
Eckmann, L
Greten, TF
Park, JM
Li, ZW
Egan, LJ
Kagnoff, MF
Karin, M
[J]. CELL, 2004, 118 (03) : 285 - 296
[9] Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
Mantovani, A
Sozzani, S
Locati, M
Allavena, P
Sica, A
[J]. TRENDS IN IMMUNOLOGY, 2002, 23 (11) : 549 - 555
[10] A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
Paik, S
Shak, S
Tang, G
Kim, C
Baker, J
Cronin, M
Baehner, FL
Walker, MG
Watson, D
Park, T
Hiller, W
Fisher, ER
Wickerham, DL
Bryant, J
Wolmark, N
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (27) : 2817 - 2826

← 1 2 →