Receptor that leaves a sour taste in the mouth

被引：132

作者：

Ugawa, S

Mianami, Y

Guo, W

Saishin, Y

Takatsuji, K

Yamamoto, T

Tohyama, M

Shimada, S

机构：

[1] Nagoya City Univ, Sch Med, Dept Anat 2, Mizuho Ku, Nagoya, Aichi 4678601, Japan

[2] Osaka Univ, Sch Med, Dept Anat & Neurosci, Osaka 5650871, Japan

[3] Osaka Univ, Fac Human Sci, Dept Behav Physiol, Osaka 5650871, Japan

来源：

NATURE | 1998年 / 395卷 / 6702期

关键词：

D O I：

10.1038/26882

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The ability to detect taste stimuli results from the activation of taste receptors located in taste-bud cells. There are several gustatory transduction mechanisms, involving membrane receptors, guanine-nucleotide-binding proteins (G proteins), second messengers and ion channels1, but genes encoding taste receptors have not yet been identified. Here we identify a complementary DNA that encodes a receptor for sour tastes.

引用

页码：555 / 556

页数：2

共 6 条

[1] The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties [J].