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Virology - HIV gets by with a lot of help from human host
被引：10
作者：
Cohen, Jon
机构：
来源：
关键词：
D O I：
10.1126/science.319.5860.143
中图分类号：
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号：
07 ;
0710 ;
09 ;
摘要：
Using cutting-edge molecular techniques, a team led by geneticist Stephen Elledge at Brigham and Women's Hospital in Boston found that the HIV virus relies on 273 human proteins to infect the host's immune cells. These so-called HIV dependency factors (HDFs) enable the virus to attach to immune cells, wiggle in, shed the protein coat that surrounds its RNA, convert that to DNA and help newly minted HIV viruses bud through the surface where they can go on and infect the other cells.
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页码：143 / 144
页数：2
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