Sex-steroid derived compounds induce sex-specific effects on autonomic nervous system function in humans

被引:63
作者
Bensafi, M
Brown, WM
Tsutsui, T
Mainland, JD
Johnson, BN
Bremner, EA
Young, N
Mauss, I
Ray, B
Gross, J
Richards, J
Stappen, I
Levenson, RW
Sobel, N
机构
[1] Univ Calif Berkeley, Dept Psychol, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Helen Wills Neurosci Inst, Berkeley, CA 94720 USA
[3] Stanford Univ, Dept Psychol, Stanford, CA 94305 USA
[4] Univ Washington, Dept Psychol, Seattle, WA 98195 USA
[5] Univ Vienna, Inst Pharmaceut Chem, A-1090 Vienna, Austria
关键词
D O I
10.1037/0735-7044.117.6.1125
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The physiological and psychological effects of 2 human sex-steroid derived compounds, 4,16-androstadien-3-one (AND) and 1,3,5(10),16-estratetraen-3-ol (EST) were measured in 24 subjects who participated in a within-subjects, double-blind experiment. A dissociation was evident in the physiological effects of AND, in that it increased physiological arousal in women but decreased it in men. EST did not significantly affect physiological arousal in women or men. Neither compound significantly affected mood. AND is an androgen derivative that is the most prevalent androstene in human male sweat, male axillary hair, and on the male axillary skin surface. The authors argue that AND's opposite effects on physiology in men and women further implicate this compound in chemical communication between humans.
引用
收藏
页码:1125 / 1134
页数:10
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