Association of Chlamydia pneumoniae with central nervous system disease

被引：37

作者：

Stratton, CW

Sriram, S

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Neurol, Nashville, TN USA

[2] Vanderbilt Univ, Med Ctr, Dept Pathol, Nashville, TN 37232 USA

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 13期

关键词：

autoimmunity; Chlamydia pneumoniae; multiple sclerosis; experimental allergic encephalomyelitis; CNS infections;

D O I：

10.1016/j.micinf.2003.09.004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chlamydia pneumoniae is a common respiratory pathogen that is now being incriminated in a number of chronic diseases. The ability of C. pneumoniae to infect and persist in macrophages makes it a likely candidate to disseminate in a number of different tissues, including those 4 of the central nervous system. This review addresses the potential and the underlying mechanisms by which C. pneumoniae infections can play a role in such diverse neurological diseases as multiple sclerosis and Alzheimer's disease. (C) 2003 Published by Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：1249 / 1253

页数：5

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