Capturing the dynamic epigenome

被引：34

作者：

Deal, Roger B. ^{[1
]}

Henikoff, Steven ^{[1
,2
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98109 USA

[2] Howard Hughes Med Inst, Seattle, WA 98109 USA

来源：

GENOME BIOLOGY | 2010年 / 11卷 / 10期

关键词：

HISTONE VARIANT H3.3; CHROMATIN-STRUCTURE; IN-VIVO; SACCHAROMYCES-CEREVISIAE; NUCLEOSOME ORGANIZATION; GENE-EXPRESSION; BUDDING YEAST; HUMAN GENOME; HUMAN-CELLS; TRANSCRIPTION;

D O I：

10.1186/gb-2010-11-10-218

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 090105 [作物生产系统与生态工程];

摘要：

Traditional methods for epigenomic analysis provide a static picture of chromatin, which is actually a highly dynamic assemblage. Recent approaches have allowed direct measurements of chromatin dynamics, providing deeper insights into processes such as transcription, DNA replication and epigenetic inheritance.

引用

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