Signaling between glia and neurons: focus on synaptic plasticity

被引:225
作者
Allen, NJ [1 ]
Barres, BA [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Neurobiol, Stanford, CA 94305 USA
关键词
D O I
10.1016/j.conb.2005.08.006
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Glial cells are now emerging from the shadows cast by their more excitable CNS counterparts. Within the developing nervous system, astrocytes and Schwann cells actively help to promote synapse formation and function, and have even been implicated in synapse elimination. In the adult brain, astrocytes respond to synaptic activity by releasing transmitters that modulate synaptic activity. Thus, glia are active participants in brain function. Many questions remain about the identity of glial-neuronal signals and their significance.
引用
收藏
页码:542 / 548
页数:7
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