Breakthrough disseminated Aspergillus ustus infection in allogeneic hematopoietic stem cell transplant recipients receiving voriconazole or caspofungin prophylaxis

被引:61
作者
Pavie, J
Lacroix, C
Hermoso, DG
Robin, M
Ferry, C
Bergeron, A
Feuilhade, M
Dromer, F
Gluckman, E
Molina, JM
Ribaud, P
机构
[1] Hop St Louis, Serv Hematol Greffe Moelle, F-75475 Paris, France
[2] Hop St Louis, Serv Malad Infect & Trop, F-75475 Paris, France
[3] Hop St Louis, Lab Parasitol Mycol, F-75475 Paris, France
[4] Hop St Louis, Serv Pneumol, F-75475 Paris, France
[5] Inst Pasteur, Ctr Natl Reference Mycol & Antifong, Unite Mycol Mol, CNRS FRE 2849, Paris, France
关键词
D O I
10.1128/JCM.43.9.4902-4904.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Aspergillus ustus is an uncommon clinical species which is poorly susceptible to antifungals. We report two cases of A. ustus infections that occurred in allogeneic stem cell transplant recipients while they were receiving either voriconazole or caspofungin. Prolonged use of these new antifungal agents may increase the risk of the emergence of resistant organisms.
引用
收藏
页码:4902 / 4904
页数:3
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