Effects of the oral spirochete Treponema denticola on interleukin-8 expression from epithelial cells

被引：24

作者：

Deng, QD ^{[1
]}

Han, Y ^{[1
]}

Xia, X ^{[1
]}

Kuramitsu, HK ^{[1
]}

机构：

[1] SUNY Buffalo, Dept Oral Biol, Buffalo, NY 14214 USA

来源：

ORAL MICROBIOLOGY AND IMMUNOLOGY | 2001年 / 16卷 / 03期

关键词：

Treponema denticola; interleukin-8; periodontitis; Porphyromonas gingivalis; Fusobacterium nucleatum;

D O I：

10.1034/j.1399-302x.2001.016003185.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

This communication demonstrates that the interaction of the oral spirochete Treponema denticola 35405 with KB epithelial cells does not lead to the induction of interleukin-8 production as occurs with a variety of other bacteria. Utilizing the dentilisin protease mutant K1 of T. denticola, this property was demonstrated to be primarily a function of the expression of the protease by strain 35405.

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收藏

页码：185 / 187

页数：3

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