Presentation of a new magnetic field therapy system for the treatment of human solid tumors with magnetic fluid hyperthermia

被引:557
作者
Jordan, A
Scholz, R
Maier-Hauff, K
Johannsen, M
Wust, P
Nadobny, J
Schirra, H
Schmidt, H
Deger, S
Loening, S
Lanksch, W
Felix, R
机构
[1] CVK, Clin Radiol, Dept Radiat Oncol, D-13353 Berlin, Germany
[2] CVK, Clin Neurol & Neurosurg, Dept Neurosurg, D-13353 Berlin, Germany
[3] CCM, Urol Clin, D-10117 Berlin, Germany
[4] INM, D-66123 Saarbrucken, Germany
关键词
interstitial hyperthermia; brain tumor; prostate carcinoma; MFH-applicator; hyperthermia; AC magnetic field; magnetic nanoparticle; glioblastoma;
D O I
10.1016/S0304-8853(00)01239-7
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Magnetic fluid hyperthermia (MFH) selectively heats up tissue by coupling alternating current (AC) magnetic fields to targeted magnetic fluids, so that boundaries of different conductive tissues do not interfere with power absorption. In this paper, a new AC magnetic field therapy system for clinical application of MFH is described. With optimized magnetic nanoparticle preparations it will be used for target-specific glioblastoma and prostate carcinoma therapy. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:118 / 126
页数:9
相关论文
共 17 条
  • [1] BREZOVICH IA, 1989, RADIOL CLIN N AM, V27, P589
  • [2] HYPERTHERMIA OF PET ANIMAL TUMORS WITH SELF-REGULATING FERROMAGNETIC THERMOSEEDS
    BREZOVICH, IA
    LILLY, MB
    MEREDITH, RF
    WEPPELMANN, B
    HENDERSON, RA
    BRAWNER, W
    SALTER, MM
    [J]. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 1990, 6 (01) : 117 - 130
  • [3] GIBBS FA, 1996, THERMORADIOTHERAPY T, V2
  • [4] GILES G, 1995, BRAIN TUMORS
  • [5] HARSH GR, 1995, BRAIN TUMORS
  • [6] Endocytosis of dextran and silan-coated magnetite nanoparticles and the effect of intracellular hyperthermia on human mammary carcinoma cells in vitro
    Jordan, A
    Scholz, R
    Wust, P
    Schirra, H
    Schiestel, T
    Schmidt, H
    Felix, R
    [J]. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 1999, 194 (1-3) : 185 - 196
  • [7] Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo
    Jordan, A
    Scholz, R
    Wust, P
    Fahling, H
    Krause, J
    Wlodarczyk, W
    Sander, B
    Vogl, T
    Felix, R
    [J]. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 1997, 13 (06) : 587 - 605
  • [8] INDUCTIVE HEATING OF FERRIMAGNETIC PARTICLES AND MAGNETIC FLUIDS - PHYSICAL EVALUATION OF THEIR POTENTIAL FOR HYPERTHERMIA
    JORDAN, A
    WUST, P
    FAHLING, H
    JOHN, W
    HINZ, A
    FELIX, R
    [J]. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 1993, 9 (01) : 51 - 68
  • [9] MAIERHAUFF K, 1996, CAR 96 COMPUTER ASSI
  • [10] MAIERHAUFF K, 1996, AKTUEL NEUROL, V23, P63