Detecting and localizing the foci in human epileptic seizures

被引:18
作者
Ben-Jacob, Eshel [1 ]
Boccaletti, Stefano [2 ,3 ]
Pomyalov, Anna [3 ]
Procaccia, Itamar [3 ]
Towle, Vernon L. [4 ]
机构
[1] Tel Aviv Univ, Sch Phys, IL-69978 Tel Aviv, Israel
[2] Embassy Italy, IL-68125 Tel Aviv, Israel
[3] Weizmann Inst Sci, Dept Phys Chem, IL-76100 Rehovot, Israel
[4] Univ Chicago, Dept Neurol, Chicago, IL 60637 USA
关键词
D O I
10.1063/1.2805658
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
We consider the electrical signals recorded from a subdural array of electrodes placed on the pial surface of the brain for chronic evaluation of epileptic patients before surgical resection. A simple and computationally fast method to analyze the interictal phase synchrony between such electrodes is introduced and developed with the aim of detecting and localizing the foci of the epileptic seizures. We evaluate the method by comparing the results of surgery to the localization predicted here. We find an indication of good correspondence between the success or failure in the surgery and the agreement between our identification and the regions actually operated on. (c) 2007 American Institute of Physics.
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页数:8
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