TNF signaling in vascular endothelial cells

被引：272

作者：

Madge, LA ^{[1
]}

Pober, JS

机构：

[1] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Interdept Program Vascular Biol & Transplantat, New Haven, CT 06520 USA

来源：

EXPERIMENTAL AND MOLECULAR PATHOLOGY | 2001年 / 70卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1006/exmp.2001.2368

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Vascular endothelium is a major target of actions of the proinflammatory cytokine tumor necrosis factor (TNF). Increasingly, the intracellular pathways that are activated in response to TNF have been elucidated. Many of these pathways have proven to be cell type-specific, requiring that observations made in other cell types be confirmed or ruled out in endothelial cells (EC). In this review the authors will summarize the state of the field, emphasizing studies in cultured human EC. (C) 2001 Academic Press.

引用

页码：317 / 325

页数：9

共 87 条

[1] Induction of stress-activated protein kinases c-Jun N-terminal kinases by the p55 tumour necrosis factor receptor does not require sphingomyelinases
Adam, D
Ruff, A
Strelow, A
Wiegmann, K
Krönke, M
[J]. BIOCHEMICAL JOURNAL, 1998, 333 : 343 - 350
[2] A novel cytoplasmic domain of the p55 tumor necrosis factor receptor initiates the neutral sphingomyelinase pathway
Adam, D
Wiegmann, K
AdamKlages, S
Ruff, A
Kronke, M
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (24) : 14617 - 14622
[3] FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase
AdamKlages, S
Adam, D
Wiegmann, K
Struve, S
Kolanus, W
SchneiderMergener, J
Kronke, M
[J]. CELL, 1996, 86 (06) : 937 - 947
[4] Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha
Alessi, DR
James, SR
Downes, CP
Holmes, AB
Gaffney, PRJ
Reese, CB
Cohen, P
[J]. CURRENT BIOLOGY, 1997, 7 (04) : 261 - 269
[5] TYR-716 IN THE PLATELET-DERIVED GROWTH-FACTOR BETA-RECEPTOR KINASE INSERT IS INVOLVED IN GRB2 BINDING AND RAS ACTIVATION
ARVIDSSON, AK
RUPP, E
NANBERG, E
DOWNWARD, J
RONNSTRAND, L
WENNSTROM, S
SCHLESSINGER, J
HELDIN, CH
CLAESSONWELSH, L
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (10) : 6715 - 6726
[6] Accommodation of vascularized xenografts: Expression of ''protective genes'' by donor endothelial cells in a host Th2 cytokine environment
Bach, FH
Ferran, C
Hechenleitner, P
Mark, W
Koyamada, N
Miyatake, T
Winkler, H
Badrichani, A
Candinas, D
Hancock, WW
[J]. NATURE MEDICINE, 1997, 3 (02) : 196 - 204
[7] TUMOR-NECROSIS-FACTOR (TNF)-ALPHA ACTIVATES C-RAF-1 KINASE VIA THE P55 TNF RECEPTOR ENGAGING NEUTRAL SPHINGOMYELINASE
BELKA, C
WIEGMANN, K
ADAM, D
HOLLAND, R
NEULOH, M
HERRMANN, F
KRONKE, M
BRACH, MA
[J]. EMBO JOURNAL, 1995, 14 (06) : 1156 - 1165
[8] A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
Black, RA
Rauch, CT
Kozlosky, CJ
Peschon, JJ
Slack, JL
Wolfson, MF
Castner, BJ
Stocking, KL
Reddy, P
Srinivasan, S
Nelson, N
Boiani, N
Schooley, KA
Gerhart, M
Davis, R
Fitzner, JN
Johnson, RS
Paxton, RJ
March, CJ
Cerretti, DP
[J]. NATURE, 1997, 385 (6618) : 729 - 733
[9] Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
Boldin, MP
Goncharov, TM
Goltsev, YV
Wallach, D
[J]. CELL, 1996, 85 (06) : 803 - 815
[10] BRADLEY JR, 1995, AM J PATHOL, V146, P27

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