Copper-mediated cross-coupling of functionalized arylmagnesium reagents with functionalized alkyl and benzylic halides

被引：77

作者：

Dohle, W ^{[1
]}

Lindsay, DM ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Inst Organ Chem, D-81377 Munich, Germany

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 18期

关键词：

D O I：

10.1021/ol0163272

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Functionalized arylmagnesium halides, prepared via an iodine-magnesium exchange, undergo a smooth cross-coupling reaction with functionalized primary alkyl iodides and benzylic bromides in the presence of CuCN . 2LiCl, either in stoichiometric (with trimethyl phosphite as an additive) or catalytic quantities.

引用

页码：2871 / 2873

页数：3

共 21 条

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