What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance

被引：75

作者：

Udy, Andrew A. ^{[1
,2
]}

Roberts, Jason A. ^{[1
,2
]}

De Waele, Jan J. ^{[5
]}

Paterson, David L. ^{[3
,4
]}

Lipman, Jeffrey ^{[1
,2
]}

机构：

[1] Royal Brisbane & Womens Hosp, Dept Intens Care Med, Herston, Qld 4029, Australia

[2] Univ Queensland, Burns Trauma & Crit Care Res Ctr, Herston, Qld, Australia

[3] Univ Queensland, Clin Res Ctr, Herston, Qld, Australia

[4] Royal Brisbane & Womens Hosp, Dept Infect Dis, Herston, Qld 4029, Australia

[5] Ghent Univ Hosp, Dept Crit Care Med, Ghent, Belgium

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2012年 / 39卷 / 06期

关键词：

INTENSIVE-CARE-UNIT; CREATININE CLEARANCE; BACTERIAL PNEUMONIA; TIGECYCLINE; RESISTANCE; CEFEPIME;

D O I：

10.1016/j.ijantimicag.2012.02.010

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

引用

页码：455 / 457

页数：3

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