Single-layer membrane valves for elastomeric microfluidic devices

被引：63

作者：

Abate, A. R. ^{[1
]}

Weitz, D. A. ^{[1
]}

机构：

[1] Harvard Univ, Sch Engn & Appl Sci, Dept Phys, Cambridge, MA 02138 USA

来源：

APPLIED PHYSICS LETTERS | 2008年 / 92卷 / 24期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1063/1.2945797

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We characterize single-layer membrane valves for elastomeric microfluidic devices. The devices are simple to fabricate using standard single-layer softlithography; moreover, they afford continuous control over flow rate. This combines the simplicity of stamped microfluidic devices with the precision control of membrane valves, which we demonstrate by steering objects in the flow using a simple device. (c) 2008 American Institute of Physics.

引用

页数：3

共 20 条

[1] High-speed microfluidic differential manometer for cellular-scale hydrodynamics [J].

Abkarian, M ;

Faivre, M ;

Stone, HA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (03) :538-542

[2] Evaluation of polydimethylsiloxane scaffolds with physiologically-relevant elastic moduli: interplay of substrate mechanics and surface chemistry effects on vascular smooth muscle cell response [J].

Brown, XQ ;

Ookawa, K ;

Wong, JY .

BIOMATERIALS, 2005, 26 (16) :3123-3129

[3]

*EPAPS, EAPPLAB92091824 EPAP, P93106

[4] Coding/decoding and reversibility of droplet trains in microfluidic networks [J].

Fuerstman, Michael J. ;

Garstecki, Piotr ;

Whitesides, George M. .

SCIENCE, 2007, 315 (5813) :828-832

[5] Microfluidic memory and control devices [J].

Groisman, A ;

Enzelberger, M ;

Quake, SR .

SCIENCE, 2003, 300 (5621) :955-958

[6] A microfluidic device for kinetic optimization of protein crystallization and in situ structure determination [J].

Hansen, CL ;

Classen, S ;

Berger, JM ;

Quake, SR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (10) :3142-3143

[7] A nanoliter-scale nucleic acid processor with parallel architecture [J].

Hong, JW ;

Studer, V ;

Hang, G ;

Anderson, WF ;

Quake, SR .

NATURE BIOTECHNOLOGY, 2004, 22 (04) :435-439

[8]

LEE CH, 2007, J MICROMECH MICROENG, V17, P93106

[9] Microfluidic valve with cored glass microneedle for microinjection [J].

Lee, S ;

Jeong, W ;

Beebe, DJ .

LAB ON A CHIP, 2003, 3 (03) :164-167

[10]

Liu J, 2002, ELECTROPHORESIS, V23, P1531, DOI 10.1002/1522-2683(200205)23:10<1531::AID-ELPS1531>3.0.CO

← 1 2 →