Multiplexing sensory molecules map protons near micellar membranes

被引：69

作者：

Uchiyama, Seiichi ^{[1
,2
]}

Iwai, Kaoru ^{[3
]}

de Silva, A. Prasanna ^{[1
]}

机构：

[1] Queens Univ Belfast, Sch Chem & Chem Engn, Belfast BT9 5AG, Antrim, North Ireland

[2] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

[3] Nara Womens Univ, Fac Sci, Dept Chem, Nara 6308506, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 25期

关键词：

fluorescence spectroscopy; fluorescent probes; micelles; molecular devices; sensors;

D O I：

10.1002/anie.200801516

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Hi-fi mapping: Multiplexing fluorescent sensors that simultaneously target proton concentration and polarity move to micellar nanospaces, self-regulate their positions, and report their pKa values and wavelengths, which are controlled by their local environments. Such sensory functions enable maps of proton gradients near micellar membranes to be drawn. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4667 / 4669

页数：3

共 37 条

[1] Molecular machines based on metal ion translocation [J].

Amendola, V ;

Fabbrizzi, L ;

Mangano, C ;

Pallavicini, P .

ACCOUNTS OF CHEMICAL RESEARCH, 2001, 34 (06) :488-493

[2] Supramolecular analytical chemistry [J].

Anslyn, Eric V. .

JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (03) :687-699

[3] Counterions in the growth of ionic micelles in aqueous electrolyte solutions: A small-angle neutron scattering study [J].

Aswal, VK ;

Goyal, PS .

PHYSICAL REVIEW E, 2000, 61 (03) :2947-2953

[4]

Balzani V., 2003, Molecular Devices and Machines, a Journey into the Nanoworld

[5] DYNAMICS OF EXCITED-STATE REACTIONS IN REVERSED MICELLES .2. PROTON-TRANSFER INVOLVING VARIOUS FLUORESCENT-PROBES ACCORDING TO THEIR SITES OF SOLUBILIZATION [J].

BARDEZ, E ;

MONNIER, E ;

VALEUR, B .

JOURNAL OF PHYSICAL CHEMISTRY, 1985, 89 (23) :5031-5036

[6] FLUORESCENT PET (PHOTOINDUCED ELECTRON-TRANSFER) SENSORS WITH TARGETING/ANCHORING MODULES AS MOLECULAR VERSIONS OF SUBMARINE PERISCOPES FOR MAPPING MEMBRANE-BOUNDED PROTONS [J].

BISSELL, RA ;

BRYAN, AJ ;

DE SILVA, AP ;

MCCOY, CP .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (04) :405-407

[7] Luminescent sensors and switches in the early 21st century [J].

Callan, JF ;

de Silva, AP ;

Magri, DC .

TETRAHEDRON, 2005, 61 (36) :8551-8588

[8] Electronically configurable molecular-based logic gates [J].

Collier, CP ;

Wong, EW ;

Belohradsky, M ;

Raymo, FM ;

Stoddart, JF ;

Kuekes, PJ ;

Williams, RS ;

Heath, JR .

SCIENCE, 1999, 285 (5426) :391-394

[9]

de Silva A. P., 1995, Angew. Chem., V107, P1889

[10] Molecular logic and computing [J].

de Silva, A. Prasanna ;

Uchiyama, Seiichi .

NATURE NANOTECHNOLOGY, 2007, 2 (07) :399-410

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