Facile synthetic method for the preparation of dithioacetals by the double conjugate addition of acetylenes bearing electron-withdrawing groups with thiols

被引：39

作者：

Kuroda, H ^{[1
]}

Tomita, I ^{[1
]}

Endo, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,RESOURCES UTILIZAT RES LAB,MIDORI KU,YOKOHAMA,KANAGAWA 226,JAPAN

来源：

SYNTHETIC COMMUNICATIONS | 1996年 / 26卷 / 08期

关键词：

D O I：

10.1080/00397919608003520

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

beta, beta-Bis(alkylmercapto)propionates were obtained by the reaction of methyl propiolates with 2 equiv. of mercaptanes in the presence of tri-n-butylphosphine in high yield. The corresponding dithioacetals could be also obtained by the conjugate addition of mercaptanes toward methyl beta-alkylmercaptoenoates, in which, tri-n-butylphosphine also catalyzed the addition of thiols.

引用

页码：1539 / 1543

页数：5

共 6 条

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