JAtlasView: a Java']Java atlas-viewer for browsing biomedical 3D images and atlases

被引:11
作者
Feng, GJ
Burton, N
Hill, B
Davidson, D
Kerwin, J
Scott, M
Lindsay, S
Baldock, R [1 ]
机构
[1] Western Gen Hosp, MRC, Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland
[2] Univ Newcastle, Int Ctr Life, Inst Human Genet, Newcastle Upon Tyne NE1 3BZ, Tyne & Wear, England
基金
英国医学研究理事会;
关键词
D O I
10.1186/1471-2105-6-47
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Background: Many three-dimensional (3D) images are routinely collected in biomedical research and a number of digital atlases with associated anatomical and other information have been published. A number of tools are available for viewing this data ranging from commercial visualization packages to freely available, typically system architecture dependent, solutions. Here we discuss an atlas viewer implemented to run on any workstation using the architecture neutral Java programming language. Results: We report the development of a freely available Java based viewer for 3D image data, descibe the structure and functionality of the viewer and how automated tools can be developed to manage the Java Native Interface code. The viewer allows arbitrary re-sectioning of the data and interactive browsing through the volume. With appropriately formatted data, for example as provided for the Electronic Atlas of the Developing Human Brain, a 3D surface view and anatomical browsing is available. The interface is developed in Java with Java3D providing the 3D rendering. For efficiency the image data is manipulated using the Woolz image-processing library provided as a dynamically linked module for each machine architecture. Conclusion: We conclude that Java provides an appropriate environment for efficient development of these tools and techniques exist to allow computationally efficient image-processing libraries to be integrated relatively easily.
引用
收藏
页数:7
相关论文
共 10 条
[1]  
Baldock RA, 1999, BIOINFORMATICS DATAB, P102
[2]   An internet-accessible database of mouse developmental anatomy based on a systematic nomenclature [J].
Bard, JBL ;
Kaufman, MH ;
Dubreuil, C ;
Brune, RM ;
Burger, A ;
Baldock, RA ;
Davidson, DR .
MECHANISMS OF DEVELOPMENT, 1998, 74 (1-2) :111-120
[3]  
GAMMA E, 1995, DESIGN PATTERNS
[4]  
GOLDSTEIN H, 1972, CLASSICAL MECH
[5]   An ontology of human developmental anatomy [J].
Hunter, A ;
Kaufman, MH ;
McKay, A ;
Baldock, R ;
Simmen, MW ;
Bard, JBL .
JOURNAL OF ANATOMY, 2003, 203 (04) :347-355
[6]   MAGNETIC-RESONANCE MICROSCOPY OF EMBRYONIC-CELL LINEAGES AND MOVEMENTS [J].
JACOBS, RE ;
FRASER, SE .
SCIENCE, 1994, 263 (5147) :681-684
[7]   DATA-STRUCTURES FOR IMAGE-PROCESSING IN A C-LANGUAGE AND UNIX ENVIRONMENT [J].
PIPER, J ;
RUTOVITZ, D .
PATTERN RECOGNITION LETTERS, 1985, 3 (02) :119-129
[8]   Optical projection tomography as a tool for 3D microscopy and gene expression studies [J].
Sharpe, J ;
Ahlgren, U ;
Perry, P ;
Hill, B ;
Ross, A ;
Hecksher-Sorensen, J ;
Baldock, R ;
Davidson, D .
SCIENCE, 2002, 296 (5567) :541-545
[9]   Computer-based three-dimensional visualization of developmental gene expression [J].
Streicher, J ;
Donat, MA ;
Strauss, B ;
Spörle, R ;
Schughart, K ;
Müller, GB .
NATURE GENETICS, 2000, 25 (02) :147-152
[10]   Phenotyping transgenic embryos: a rapid 3-D screening method based on episcopic fluorescence image capturing [J].
Weninger, WJ ;
Mohun, T .
NATURE GENETICS, 2002, 30 (01) :59-65