Use of single nucleotide polymorphisms in the plcR gene for specific identification of Bacillus anthracis

被引：58

作者：

Easterday, WR

Van Ert, MN

Simonson, TS

Wagner, DM

Kenefic, LJ

Allender, CJ

Keim, P

机构：

[1] No Arizona Univ, Dept Biol Sci, Flagstaff, AZ 86011 USA

[2] Translat Genom Res Inst, Phoenix, AZ 85004 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 04期

关键词：

D O I：

10.1128/JCM.43.4.1995-1997.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A TaqMan-minor groove binding assay designed around a nonsense mutation in the plcR gene was used to genotype Bacillus anthracis, B. cereus, and B. thuringiensis isolates. The assay differentiated B. anthracis from these genetic near-neighbors and determined that the nonsense mutation is ubiquitous across 89 globally and genetically diverse B. anthracis strains.

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页码：1995 / 1997

页数：3

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