Antimicrobial resistance of Pseudomonas aeruginosa biofilms

被引：393

作者：

Drenkard, E ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 13期

关键词：

Pseudomonas aeruginosa; biolilms; antimicrobial resistance;

D O I：

10.1016/j.micinf.2003.08.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Resistance to antimicrobial agents is the most important feature of biofilm infections. As a result, infections caused by bacterial biofilms are persistent and very difficult to eradicate. Although several mechanisms have been postulated to explain reduced susceptibility to antimicrobials in bacterial biofilms, it is becoming evident that biofilm resistance is multifactorial. The contribution of each of the different mechanisms involved in biofilm resistance is now beginning to emerge. (C) 2003 Editions scientitiques et medicales Elsevier SAS. All rights reserved.

引用

页码：1213 / 1219

页数：7

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