Macrolide resistance in Streptococcus pneumoniae in Hong Kong

被引：29

作者：

Ip, M ^{[1
]}

Lyon, DJ

Yung, RWH

Chan, C

Cheng, AFB

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Microbiol, Shatin, Hong Kong, Peoples R China

[2] Pamela Youde Nethersole Eastern Hosp, Hong Kong, Hong Kong, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 05期

关键词：

D O I：

10.1128/AAC.45.5.1578-1580.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Erythromycin resistance rates among penicillin-susceptible Streptococcus pneumoniae were 38 and 92% among penicillin-intermediate and -resistant S. pneumoniae isolates from Hong Kong, respectively, and 27% (43 of 158) of the isolates showed the MLSB phenotype, and the majority carried the ermB gene; 73% (115 of 158) displayed the M phenotype, and all possessed the mef gene. The MLSB phenotype was predominant in penicillin-susceptible, macrolide-resistant isolates and in penicillin-nonsusceptible isolates of serotype 6B, whilst the M phenotype was predominant in penicillin-intermediate or -resistant isolates belonging to serotype 23F or 19F. Extensive spread of clones of drug-resistant pneumococci has led to the widespread presence of macrolide resistance in S. pneumoniae in Hong Kong.

引用

页码：1578 / 1580

页数：3

共 17 条

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