Biological efficacy of electroless-deposited silver on plasma activated polyurethane

被引:123
作者
Gray, JE
Norton, PR [1 ]
Alnouno, R
Marolda, CL
Valvano, MA
Griffiths, K
机构
[1] Univ Western Ontario, Dept Chem & Interface Sci, London, ON N6A 5B7, Canada
[2] Univ Western Ontario, Dept Microbiol & Immunol, London, ON N6A 5B7, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
antibacterial; silver; coating; surface modification; catheters; polyurethane;
D O I
10.1016/S0142-9612(03)00057-7
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Silver coating of catheters has been shown to have inhibitory effects on bacterial growth and adhesion to catheter surfaces. In this study, plasma-modification was used to enhance the adhesion of an electroless silver coating on polyurethane. Both the antibacterial and antiadhesive properties of these coatings were investigated. Bacterial growth was inhibited in cultures exposed to silver-treated polyurethane compared to unmodified polyurethane. Higher growth inhibition was observed for polyurethane surfaces with lower silver coverage. Bacterial adhesion was completely inhibited on all silver-coated surfaces. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2759 / 2765
页数:7
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