Do-all receptor takes on coagulation, inflammation

被引：53

作者：

Esmon, C ^{[1
]}

机构：

[1] Oklahoma Med Res Fdn, Howard Hughes Med Inst, Oklahoma City, OK 73104 USA

来源：

NATURE MEDICINE | 2005年 / 11卷 / 05期

关键词：

D O I：

10.1038/nm0505-475

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

How many critical functions can be jammed into one receptor? New work on thrombomodulin explores the limits. This already overtaxed protein binds HMGB1, a molecule that contributes to sepsis and other inflammatory conditions.

引用

页码：475 / 477

页数：4

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