Long-term effect of botulinum toxin on impairment and functional health in cervical dystonia

被引:45
作者
Brans, JWM [1 ]
Lindeboom, R [1 ]
Aramideh, M [1 ]
Speelman, JD [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Neurol H2 214, NL-1100 DE Amsterdam, Netherlands
关键词
D O I
10.1212/WNL.50.5.1461
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We investigated the long-term effect of botulinum toxin type A (BTA) on impairment as well as functional health in terms of disability, handicap, and quality of life in 64 patients with cervical dystonia. These patients, who first participated in a double-blind trial, were followed for another 12 months. Fifty-four patients continued treatment after 12 months of follow-up and showed improvement on all scales. Furthermore, this effectiveness appeared to increase during follow-up, which suggests a cumulative clinical effect of BTA.
引用
收藏
页码:1461 / 1463
页数:3
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