The spatial and temporal expression pattern of Nesp and its antisense Nespas, in mid-gestation mouse embryos

被引：13

作者：

Ball, ST ^{[1
]}

Williamson, CM ^{[1
]}

Hayes, C ^{[1
]}

Hacker, T ^{[1
]}

Peters, J ^{[1
]}

机构：

[1] MRC, Mammalian Genet Unit, Didcot OX11 0RD, Oxon, England

来源：

MECHANISMS OF DEVELOPMENT | 2001年 / 100卷 / 01期

关键词：

Nesp; Nespas; imprinting; limb bud; progress zone; marginal vein; principal artery; neural tube;

D O I：

10.1016/S0925-4773(00)00490-1

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We describe the spatiotemporal expression pattern of Nesp, and its antisense transcript, Nespas. We found non-complementary expression of these two oppositely imprinted transcripts during mouse embryogenesis, in a number of forming embryonic structures. Nesp expression was primarily seen in the somites and vasculature, whereas Nespas was mainly detected in the progress zone, mesenchyme and ectoderm of the limb, and the neural tube. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：79 / 81

页数：3

共 8 条

[1] Competition - a common motif for the imprinting mechanism?
Barlow, DP
[J]. EMBO JOURNAL, 1997, 16 (23) : 6899 - 6905
[2] Ischia R, 1997, J BIOL CHEM, V272, P11657
[3] Identification of imprinted loci by methylation-sensitive representational difference analysis: Application to mouse distal chromosome 2
Kelsey, G
Bodle, D
Miller, HJ
Beechey, CV
Coombes, C
Peters, J
Williamson, CM
[J]. GENOMICS, 1999, 62 (02) : 129 - 138
[4] Pig splenic nerve: peptides derived from chromogranins by proteolytic processing during axonal transport
Lovisetti-Scamihorn, P
Liang, F
Leitner, B
De Potter, W
Winkler, H
[J]. REGULATORY PEPTIDES, 1999, 79 (01) : 63 - 67
[5] Relative amounts and molecular forms of NESP55 in various bovine tissues
Lovisetti-Scamihorn, P
Fischer-Colbrie, R
Leitner, B
Scherzer, G
Winkler, H
[J]. BRAIN RESEARCH, 1999, 829 (1-2) : 99 - 106
[6] A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2
Peters, J
Wroe, SF
Wells, CA
Miller, HJ
Bodle, D
Beechey, CV
Williamson, CM
Kelsey, G
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (07) : 3830 - 3835
[7] WILKINSON DG, 1992, IN SITU HYBRIDIZATIO
[8] An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus
Wroe, SF
Kelsey, C
Skinner, JA
Bodle, D
Ball, ST
Beechey, CV
Peters, J
Williamson, CM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (07) : 3342 - 3346

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