beadarray:: R classes and methods for Illumina bead-based data

被引：364

作者：

Dunning, Mark J. ^{[1
]}

Smith, Mike L. ^{[1
]}

Ritchie, Matthew E. ^{[1
]}

Tavare, Simon ^{[1
]}

机构：

[1] Univ Cambridge, Li Ka Shing Ctr, CRUK Cambridge Res Inst, Dept Oncol, Cambridge CB2 0RE, England

来源：

BIOINFORMATICS | 2007年 / 23卷 / 16期

关键词：

D O I：

10.1093/bioinformatics/btm311

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The R/Bioconductor package beadarray allows raw data from Illumina experiments to be read and stored in convenient R classes. Users are free to choose between various methods of image processing, background correction and normalization in their analysis rather than using the defaults in Illumina's proprietary software. The package also allows quality assessment to be carried out on the raw data. The data can then be summarized and stored in a format which can be used by other R/Bioconductor packages to perform downstream analyses. Summarized data processed by Illumina's BeadStudio software can also be read and analysed in the same manner. Availability: The beadarray package is available from the Bioconductor web page at www.bioconductor.org. A user's guide and example data sets are provided with the package. Contact: md392@cam.ac.uk

引用

页码：2183 / 2184

页数：2

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