Advantages and disadvantages of nuclear magnetic resonance spectroscopy as a hyphenated technique

被引：98

作者：

Elipe, MVS ^{[1
]}

机构：

[1] Merck Res Labs, Dept Drug Metab, Rahway, NJ 07065 USA

来源：

ANALYTICA CHIMICA ACTA | 2003年 / 497卷 / 1-2期

关键词：

hyphenated analytical techniques; structure elucidation of organic compounds; review; NMR; LC-NMR; LC-MS-NMR; flavonoids; metabolites;

D O I：

10.1016/j.aca.2003.08.048

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A general overview of the advancements and applications of nuclear magnetic resonance (NMR) hyphenated with other analytical techniques is given from a practical point of view. Details on the advantages and disadvantages of the hyphenation of NMR with liquid chromatography as LC-NMR and also with mass spectrometry as LC-MS-NMR are demonstrated with two examples. Current developments of NMR with other analytical separation techniques, especially with capillary liquid chromatography (capLC) are discussed. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：1 / 25

页数：25

共 102 条

[1] Liquid chromatography-nuclear magnetic resonance spectroscopy [J].