A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor

被引：54

作者：

Parker, MA

Marona-Lewicka, D

Lucaites, VL

Nelson, DL

Nichols, DE ^{[1
]}

机构：

[1] Purdue Univ, Sch Pharm & Pharmacal Sci, Dept Med Chem & Mol Pharmacol, W Lafayette, IN 47907 USA

[2] Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1998年 / 41卷 / 26期

关键词：

D O I：

10.1021/jm9803525

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：5148 / 5149

页数：2

共 13 条

[1] THE ROLE OF THE 5-HT2A AND 5-HT2C RECEPTORS IN THE STIMULUS EFFECTS OF HALLUCINOGENIC DRUGS .1. ANTAGONIST CORRELATION-ANALYSIS
FIORELLA, D
RABIN, RA
WINTER, JC
[J]. PSYCHOPHARMACOLOGY, 1995, 121 (03) : 347 - 356
[2] BEHAVIORAL AND SEROTONIN RECEPTOR PROPERTIES OF 4-SUBSTITUTED DERIVATIVES OF THE HALLUCINOGEN 1-(2,5-DIMETHOXYPHENYL)-2-AMINOPROPANE
GLENNON, RA
YOUNG, R
BENINGTON, F
MORIN, RD
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (10) : 1163 - 1168
[3] Johnson MP, 1996, N-S ARCH PHARMACOL, V354, P205
[4] BINDING TO THE SEROTONIN 5-HT2 RECEPTOR BY THE ENANTIOMERS OF I-125 DOI
JOHNSON, MP
HOFFMAN, AJ
NICHOLS, DE
MATHIS, CA
[J]. NEUROPHARMACOLOGY, 1987, 26 (12) : 1803 - 1806
[5] [I-125]-2-(2,5-DIMETHOXY-4-IODOPHENYL)AMINOETHANE ([I-125]-2C-I) AS A LABEL FOR THE 5-HT2 RECEPTOR IN RAT FRONTAL-CORTEX
JOHNSON, MP
MATHIS, CA
SHULGIN, AT
HOFFMAN, AJ
NICHOLS, DE
[J]. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1990, 35 (01) : 211 - 217
[6] LITCHFIELD JT, 1949, J PHARMACOL EXP THER, V96, P99
[7] Dihydrobenzofuran analogues of hallucinogens .3. Models of 4-substituted (2,5-dimethoxyphenyl)alkylamine derivatives with rigidified methoxy groups
Monte, AP
MaronaLewicka, D
Parker, MA
Wainscott, DB
Nelson, DL
Nichols, DE
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (15) : 2953 - 2961
[8] Dihydrobenzofuran analogues of hallucinogens .4. Mescaline derivatives
Monte, AP
Waldman, SR
MaronaLewicka, D
Wainscott, DB
Nelson, DL
SandersBush, E
Nichols, DE
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (19) : 2997 - 3008
[9] Nichols D. E., 1984, HALLUCINOGENS NEUROC, P95
[10] ASYMMETRIC SYNTHESIS OF PSYCHOTOMIMETIC PHENYLISOPROPYLAMINES
NICHOLS, DE
BARFKNEC.CF
RUSTERHO.DB
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (05) : 480 - 483

← 1 2 →