The Alzheimer family of diseases: Many etiologies, one pathogenesis?

[1] *ALZH DIS COLL GRO, 1996, NAT GENET, V11, P219

[2] Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo [J]. NEURON, 1996, 17 (05) : 1005 - 1013

[3] Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice [J]. NATURE MEDICINE, 1997, 3 (01) : 67 - 72

[4] The presenilin genes: A new gene family involved in Alzheimer disease pathology [J]. HUMAN MOLECULAR GENETICS, 1996, 5 : 1449 - 1455

[5] Increased amyloid-beta 42(43) in brains of mice expressing mutant presenilin 1 [J]. NATURE, 1996, 383 (6602) : 710 - 713

[6] ALZHEIMER-TYPE NEUROPATHOLOGY IN TRANSGENIC MICE OVEREXPRESSING V717F BETA-AMYLOID PRECURSOR PROTEIN [J]. NATURE, 1995, 373 (6514) : 523 - 527

[7] SEGREGATION OF A MISSENSE MUTATION IN THE AMYLOID PRECURSOR PROTEIN GENE WITH FAMILIAL ALZHEIMERS-DISEASE [J]. NATURE, 1991, 349 (6311) : 704 - 706

[8] AMYLOID DEPOSITION AS THE CENTRAL EVENT IN THE ETIOLOGY OF ALZHEIMERS-DISEASE [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1991, 12 (10) : 383 - 388

[9] HARDY J, 1997, IN PRESS TRENDS NEUR

[10] Correlative memory deficits, A beta elevation, and amyloid plaques in transgenic mice [J]. SCIENCE, 1996, 274 (5284) : 99 - 102

[1] *ALZH DIS COLL GRO, 1996, NAT GENET, V11, P219

[2] Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo [J]. NEURON, 1996, 17 (05) : 1005 - 1013

[3] Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice [J]. NATURE MEDICINE, 1997, 3 (01) : 67 - 72

[4] The presenilin genes: A new gene family involved in Alzheimer disease pathology [J]. HUMAN MOLECULAR GENETICS, 1996, 5 : 1449 - 1455

[5] Increased amyloid-beta 42(43) in brains of mice expressing mutant presenilin 1 [J]. NATURE, 1996, 383 (6602) : 710 - 713

[6] ALZHEIMER-TYPE NEUROPATHOLOGY IN TRANSGENIC MICE OVEREXPRESSING V717F BETA-AMYLOID PRECURSOR PROTEIN [J]. NATURE, 1995, 373 (6514) : 523 - 527

[7] SEGREGATION OF A MISSENSE MUTATION IN THE AMYLOID PRECURSOR PROTEIN GENE WITH FAMILIAL ALZHEIMERS-DISEASE [J]. NATURE, 1991, 349 (6311) : 704 - 706

[8] AMYLOID DEPOSITION AS THE CENTRAL EVENT IN THE ETIOLOGY OF ALZHEIMERS-DISEASE [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1991, 12 (10) : 383 - 388

[9] HARDY J, 1997, IN PRESS TRENDS NEUR

[10] Correlative memory deficits, A beta elevation, and amyloid plaques in transgenic mice [J]. SCIENCE, 1996, 274 (5284) : 99 - 102