Bacterial infection - For whom the bell tolls

被引：25

作者：

Gerard, C ^{[1
]}

机构：

[1] Harvard Univ, Childrens Hosp, Sch Med, Perlmutter Lab, Boston, MA 02115 USA

来源：

NATURE | 1998年 / 395卷 / 6699期

关键词：

D O I：

10.1038/26104

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The outer membranes of certain bacteria contain lipopolysaccharide (LPS). This is a glycolipid that can induce the host's immune system to produce cytokines, which, if left unchecked, can lead to septic shock and death. The human receptor for LPS has now been identified as a protein called Toll-like receptor 2, and theDrosophilahomologue of this protein is already known to be involved in defence against fungal infections.

引用

页码：217 / +

页数：2

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